The Naples Metro Lines 1 and 6 are two significant infrastructural projects extending approximately 18 km and 5.5 km, connecting nineteen and eight stations within the city, respectively. Both projects are situated in a complex geological context, characterized by pyroclastic soils, rocks and marine sands. This paper focuses on the monitoring of subsidence around the Line 1 Toledo station and Line 6 San Pasquale station. Traditional monitoring operations are compared with satellite-based analyses to evaluate the effects of subsidence. Data obtained from satellite monitoring, with DInSAR (Differential Synthetic Aperture Radar Interferometry) technique, are compared with traditional monitoring results to identify any critical issues that may necessitate further investigation. The goal is to assess the suitability of satellite monitoring in the context of deep excavation works and to quantify the reliability of DInSAR in both presented circumstances. For the analysis, C-Band ENVISAT (2002–2010) and X-Band COSMO-SkyMed data (2011–2014, 2016–2019, 2021–2022) are used for Line 1 stations, while only X-Band COSMO-SkyMed data are employed for Line 6 stations (2011–2013, 2013–2016, 2011–2016).