The southwest Sabzevar basin in northeast Iran is one of the most important areas for volcanogenic stratiform manganese deposits. The Mohammadabad Mn deposit, found in this basin, is hosted by the upper late Cretaceous marly tuffs in a region that has an active history of tectonism. Their geology, mineralogy and geochemistry, including major, trace and rare earth elements (REE), are described in this work. The main ore minerals include pyrolusite, psilomelane, cryptomelane, with minor braunite and manganite. Four styles of manganese mineralization are recognized: (1) layered; (2) nodular; (3) disseminated; and (4) replacement to massive. Regardless of style, pyrolusite, psilomelane, and cryptomelane usually tend to parallel the stratification of sediments, while braunite veins occur in high angle fractures. The replacement of radiolarian and foraminiferal fossils by manganese minerals during diagenesis near the seawater-sediment interface suggests that mineralization occurred in oxygen-rich conditions under the influence of low-temperature hydrothermal fluids. The geochemistry of trace elements of manganese oxides and rare earth elements gives clear evidence of hydrothermal-exhalative origin for Mohammadabad deposit. In general, ore minerals have Co/Ni ratios above 0.12, and U/Th ratios vary from 0.13 to 11.29. The presence of negative Eu anomalies in manganese minerals shows that the ore-forming fluids were generally low-temperature and oxic during mineral formation. In-situ mineralogy studies based on SEM-EDS have distinguished syngeneic and diagenetic Mn systems during the formation of manganese mineralization. The Mohammadabad deposit is considered a typical case of volcanic hydrothermal exhalative-diagenetic Mn mineralization, in which minerals deposited when hydrothermal fluid was released from oxic to dysoxic water columns. [Display omitted] • Mohammadabad Mn deposit is associated with the Late Cretaceous volcano-sedimentary sequence. • Geochemistry of manganese oxides give clear evidence of hydrothermal origin. • The Mohammadabad deposit is considered a typical case of sedimentary hydrothermal exhalative Mn mineralization.